Emma writes...
Thoughts, resources and comment from the NHD Editor.
Going Mediterranean – the best diet for ageing well?
Another run around the sun and here we are, starting a New Year once again. Time marches on regardless, where new ideas and innovations arise, whilst other things begin to age and feel the effects of time passing by. And that includes us!
Ageing is part of the cycle of life and eventually impacts us all. Whilst we can’t beat the ageing process we can adopt healthier lifestyles to age well.
Worldwide, people are living longer and by 2030, one in six people across the globe will be 60 years or older.(1) This will mean that the population of those over the age of 60 will have increased from 1 billion in 2020 to 1.4 billion in 2030 and it’s expected that by 2050, the global population of over 60s will reach 2.1 billion.(1)
Support and advice for ageing well aimed at people aged over 70 years is available from NHS England.(2) It includes information and services regarding oral, auditory, eye and feet care, preventing falls, plus keeping warm and safe at home. It also covers eating well, keeping active and cognitive health.
Keeping your noggin healthy
Brain and mental health are key aspects of ageing well, which can be influenced by diet and other lifestyle choices such as smoking and alcohol consumption.
Back in May 2024, Emma Writes focused on dementia awareness,(3) giving an overview of the condition and the current guidance on reducing risk and dietary considerations. To recap from that blog, ‘it’s estimated that by 2030, over one million people in the UK will have a diagnosis of dementia and, currently, 1 in 11 people over the age of 65 have dementia in the UK.4 Around 65% of those living with dementia in the UK are women.4 Dementia can affect people at any age but it is most common in those over the age of 65.’
With the growing ageing population and with it, the incidence of dementia, where does diet play a role in this area?
Be EPIC?
At the BAPEN conference held in November 2024, researcher and expert speaker, Professor Anne Marie Minihane (Professor of Nutrigenetics, University of East Anglia), shared key points from research which looked at the nutrition and cognition in later life,(5) specifically the role of the Mediterranean diet (MedDiet).
Results from the large multicentre cohort EPIC – Norfolk study(6) was published in 2019 and evaluated MedDiet adherence and cognitive function in older UK adults. Data from the study showed that a higher adherence to the MedDiet is associated with better cognitive function and a lower risk of poor cognition in older UK adults.
Further research via the MEDEx-UK trial(7) was presented by Prof Minihan, which has provided insights into the potential impact that MedDiet +/- physical activity can have on cognitive health in older adults at risk of dementia.
Better adherence to MedDiet and physical activity does help to improve cognitive function. When comparing participants who adhered to the MedDiet versus participants who followed a more traditional Western diet, improvements in mood and anxiety were significantly different between the two groups and differences could be seen within just five days.
Sounds fishy?
It is acknowledged that DHA contributes to the maintenance of normal brain function and has other health benefits.(8)
The role of docosahexaenoic acid (DHA) in cognitive health as we age was also discussed by Professor Minihane during her session. She highlighted that depletion of DHA within the brains occurs as we age, particularly affecting women of menopausal age.9 However, there is mixed RCT evidence for introducing DHA supplementation as a preventative measure for dementia and there is limited data available regarding effective dosages, frequency and age for intervention.(9)
WHAT IS THE MEDITERRANEAN DIET?
The MedDiet is based on the traditional eating habits of people from coastal Mediterranean countries including Greece, Southern Italy, France and Spain. The diet promotes the consumption of plenty of plant-based foods – fruits, vegetables, beans, pulses, seeds, nuts and whole grains. It also includes the use of olive oil and a moderate intake of lean protein sources such as chicken, fish and eggs. Red or processed meats feature less in this diet and are kept to a minimum.
Typically, the MedDiet is low in saturated fats, high in monounsaturated fatty acids (MUFA), low in salt, high in fibre and rich in antioxidants and omega-3 fats.
Here are some useful links for more on the MedDiet:
British Dietetic Association - Mediterranean-diet.pdf
Heart UK - The Mediterranean diet
British Heart Foundation - Watch: What is the Mediterranean diet? - Heart Matters - BHF
Ageing doesn’t mean being frail
Frailty is a common clinical state seen in those who are older. According to Age UK, approximately 10% of people aged 65 or over live with frailty, and this increases to between 25 and 50% in those who are aged 85 or above.(10)
Frailty can be defined as ‘a clinically recognisable state of increased vulnerability resulting from aging associated decline in reserve and function across multiple physiologic systems such that the ability to cope with every day or acute stressors is compromised.’(11)
Once again, the MedDiet has been of interest in this area and research has shown some promising results regarding its potentially protective effects. A systematic review and meta-analysis conducted by Rashidi et al(12) aimed to assess the relationship between dietary patterns and frailty. Thirteen studies were identified, which were cohort or cross-sectional, examining dietary patterns in relation to risk of frailty.
It was particularly noted that sub-group studies from Mediterranean countries highlighted beneficial effects in reducing the risk of frailty. Higher adherence to a healthy dietary pattern was associated with lower odds of frailty, with indications that a diet high in fruit, vegetables and wholegrains may be associated with reduced risk of frailty.
Further evidence to support the use of the MedDiet in reducing the risk of frailty was demonstrated by Dominguez et al in 2023,(13) who also conducted a systematic review and meta-analysis that aimed to explore the association between the MedDiet and the risk of frailty in older adults. Key findings from this work show that the MedDiet is a high-quality diet with the greatest evidence of association with reduced frailty risk. The researchers concluded that their results confirmed a strong association between adhering to the MedDiet and a lower incidence of frailty.
End note
Whilst there are still many questions to be answered in relation to the best way to age and which approaches are the most beneficial, there is some data to support a high-quality MedDiet diet for ageing well. More research is emerging regarding diet and the impact it can have on how we age in the future. Potentially arming us with more knowledge to further prevent or reduce some of the challenges of ageing. The unanswered questions are there to be investigated with time but there’s a good indication that eating well has the potential to help us to age well.
Emma has been a Registered Dietitian for over 18 years and has experience in adult and paediatric dietetics. She has been the Editor of NHD for nine years, steering the editorial content and supporting the production process.
Emma currently works in industry.
Emma Coates, RD
References
WHO (2024). Ageing and health. Ageing and health
NHS England (2019). A practical guide to healthy ageing. a-practical-guide-to-healthy-ageing.pdf
NHD (2024). Emma Writes – Dementia: it's not all in the mind!. https://www.nhdmag.co.uk/emma-writes-dementia-awareness
NHS (2023). What is dementia. https://www.nhs.uk/conditions/dementia/about-dementia/what-is-dementia/
BAPEN (2024). BAPEN annual conference 2024 programme. bapen-2024-programme-v11.pdf
Shannon et al (2019). Mediterranean diet adherence and cognitive function in older UK adults: the European Prospective Investigation into Cancer and Nutrition-Norfolk (EPIC-Norfolk) Study. Mediterranean diet adherence and cognitive function in older UK adults: the European Prospective Investigation into Cancer and Nutrition–Norfolk (EPIC-Norfolk) Study - ScienceDirect
Shannon et al (2021). Feasibility and acceptability of a multi-domain intervention to increase Mediterranean diet adherence and physical activity in older UK adults at risk of dementia: protocol for the MedEx-UK randomised controlled trial. Feasibility and acceptability of a multi-domain intervention to increase Mediterranean diet adherence and physical activity in older UK adults at risk of dementia: protocol for the MedEx-UK randomised controlled trial - PMC
EFSA (2011) Scientific Opinion on the substantiation of health claims related to docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and brain, eye and nerve development (ID 501, 513, 540), maintenance of normal brain function (ID 497, 501, 510, 513, 519, 521, 534, 540, 688, 1323, 1360, 4294), maintenance of normal vision (ID 508, 510, 513, 519, 529, 540, 688, 2905, 4294), maintenance of normal cardiac function (ID 510, 688, 1360), “maternal health; pregnancy and nursing” (ID 514), “to fulfil increased omega-3 fatty acids need during pregnancy” (ID 539), “skin and digestive tract epithelial cells maintenance” (ID 525), enhancement of mood (ID 536), “membranes cell structure” (ID 4295), “anti-inflammatory action” (ID 4688) and maintenance of normal blood LDL-cholesterol concentrations (ID 4719) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. DHA/EPA related health claims | EFSA
Saleh and Manihane (2021). Fish, n-3 fatty acids, cognition and dementia risk: not just a fishy tale. Fish, n-3 fatty acids, cognition and dementia risk: not just a fishy tale | Proceedings of the Nutrition Society | Cambridge Core
Age UK (2020). Understanding frailty. What is frailty? | Age UK
Xue (2011). The Frailty Syndrome: Definition and Natural History. The Frailty Syndrome: Definition and Natural History - Clinics in Geriatric Medicine
Rashidi et al (2019). Dietary patterns and frailty: a systematic review and meta-analysis. Dietary patterns and frailty: a systematic review and meta-analysis | Nutrition Reviews | Oxford Academic
Dominguez et al (2023). Rationale of the association between Mediterranean diet and the risk of frailty in older adults and systematic review and meta-analysis. Rationale of the association between Mediterranean diet and the risk of frailty in older adults and systematic review and meta-analysis - ScienceDirect